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What is hyaluronic acid?
Hyaluronic acid is a natural substance found within the human body and a major component of normal synovial fluid. It stores moisture, acting as a lubricant between body tissues to prevent the build-up of friction.
In a healthy joint, your synovial fluid acts as a shock absorber, providing lubrication and allowing your bones to glide smoothly against each other without rubbing together.
If you have osteoarthritis, the hyaluronic acid in the synovial fluid breaks down, losing some of its elastic properties. The synovial fluid can no longer cushion the joints, and this can cause the pain and stiffness usually associated with osteoarthritis.
I have a question about Durolane injections
Meet our experts
Nik Bakti
Consultant Orthopaedic Surgeon
Mr Bakti specialises in shoulder procedures.
Language(s): English
Location(s): Kent
Alex Chipperfield
Consultant Orthopaedic Surgeon
Mr Chipperfield's specialties include hip and knee replacement, including ROSA knee, revision hip and knee replacement, Arthrosamid® injections and more.
Language(s): English
Location(s): Kent | London
Baljinder Singh Dhinsa
Consultant Orthopaedic Surgeon
Mr Singh Dhinsa's specialties include hallux valgus surgery and management of foot and ankle conditions
Language(s): English, Punjabi
Location(s): Kent
Michael Dunning
Consultant Orthopaedic Surgeon
Mr Dunning's specialities include hallux valgus surgery, sports injuries of the foot and ankle and arthrodesis surgery.
Language(s): English
Location(s): Kent
Richard Goddard
Consultant Orthopaedic Surgeon
Mr Goddard's specialties include total knee replacement and Signature total knee replacement.
Language(s): English
Location(s): Kent
Christopher James
Orthopaedic and trauma consultant
Mr James' specialties include hand and wrist surgery, both open and arthroscopic procedures.
Language(s): English
Location(s): Kent
Mark Jones
Consultant Orthopaedic Surgeon
Mr Mark Jones specialises in knee replacement and knee surgeries, including ROSA knee, as well as Arthrosamid® injections.
Language(s): English
Location(s): Kent
Daniel Neen
Consultant Orthopaedic Surgeon
Mr Neen's specialities include clavicle surgery, shoulder surgery, elbow surgery and wrist and hand surgery.
Language(s): English
Location(s): Kent
Matthew Oliver
Consultant Trauma and Orthopaedic Surgeon
Mr Oliver's specialties include total hip and knee replacement, including ROSA knee, enhanced recovery protocols and Dupuytrens disease.
Language(s): English
Location(s): Kent
Kumar Reddy
Associate Specialist Surgeon
Mr Reddy specialises in total hip and knee replacements, revision joint replacements, ACL reconstruction, and more.
Language(s): English
Location(s): Kent
Andrew Smith
Consultant Orthopaedic Surgeon
Mr Andrew Smith is a Consultant Orthopaedic Surgeon who specialises in carpal tunnel syndrome, trigger finger, hand and wrist arthritis
Language(s): English
Location(s): Kent
Crispin Southgate
Consultant Orthopaedic Surgeon
Mr Southgate's specialities include foot and ankle conditions - covering sports injuries and more.
Language(s): English
Location(s): Kent
Hemant Thakral
Consultant Orthopaedic Surgeon
Mr Thakral's specialties include shoulder arthroscopic surgery, complex joint replacements for arthritis and trauma.
Language(s): English
Location(s): Kent
Raman Thakur
Consultant Orthopaedic Surgeon
Mr Thakur's specialties include hip and knee replacement, ACL reconstruction and general orthopaedics.
Language(s): English
Location(s): Kent
Dimitri Yanni
Consultant Orthopaedic Surgeon
Mr Yanni's specialties include elbow, hand and wrist surgery.
Language(s): English, French
Location(s): Kent
William Dunnet
Consultant Orthopaedic Surgeon
Mr Dunnet's specialities include hip surgery, patella realignment and lower limb procedures.
Language(s): English
Location(s): Kent
Contact us about Durolane injections
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References
1. Zhang H, Zhang K, Zhang X, et al. Comparison of two hyaluronic acid formulations for safety and efficacy (CHASE) study in knee osteoarthritis: a multicenter, randomized, double-blind, 26-week non-inferiority trial comparing Durolane to Artz. Arthritis Res Ther. 2015;17(1):51. doi:10.1186/s13075-015-0557-x
2. Krocker D, Matziolis G, Tuischer J, et al. Reduction of arthrosis associated knee pain through a single intra-articular injection of synthetic hyaluronic acid. Z Rheumatol. 2006;65(4):327-31. doi:10.1007/s00393-006- 0063-2
3. Leighton R, Åkermark C, Therrien R, et al. NASHA hyaluronic acid vs. methylprednisolone for knee osteoarthritis: a prospective, multicentre, randomized, non-inferiority trial. Osteoarthritis Cartilage. 2014;22(1):17- 25. doi:10.1016/j. joca.2013.10.009
4. Romero Jurado M, Enrique Fidalgo A, Rodríguez Villar V, Mar Medina J, Soler López B. Factors related with the time to surgery in waiting-list patients for knee prostheses. Reumatol Clin. 2013;9(3):148–55
5. DUROLANE [package insert]. Durham, NC: Bioventus LLC; 2019.